A Roman cognomen, notably borne by Lucius Annaeus Seneca, a Roman stoic philosopher, dramatist, and statesman.
The Iroquoian language of the Seneca people.
A proper noun "seneca" represents a number of places in the united states, including cities, towns, and unincorporated communities in kansas, new york, and various counties in wisconsin.
A member of a tribe of Native Americans in western New York state.