(transitive) To tangle up; to twist or interweave in such a manner as not to be easily separated.
(transitive) To involve in such complications as to render extrication difficult.
(transitive, figuratively) To ensnare.
(transitive) To involve in difficulties or embarrassments; to embarrass, puzzle, or distract by adverse or perplexing circumstances, interests, demands, etc.; to hamper; to bewilder.