To make something holy by religious rite, sanctify.

To make the sign of the cross upon, so as to sanctify.

To invoke divine favor upon.

To honor as holy, glorify; to extol for excellence.

To esteem or account happy; to felicitate.

(obsolete) To wave; to brandish.

(Perl programming, transitive, past tense only blessed) To turn (a reference) into an object.

(archaic, with from) To secure, defend, or prevent from.

(MTE, slang) To give or send.

(UK, Canada, informal) Used as an expression of endearment, gratitude, or (ironically) belittlement.